KU-177

Overview

KU-177 is a potent inhibitor of Hsp90 ATPase homologue 1 ( Aha1 ), ablates Aha1 -driven enhancement of Hsp90-dependent tau aggregation. KU-177 also disrupts Aha1 / Hsp90 interactions ( IC 50 =4.08 μM) without inhibition of Hsp90’s ATPase activity. KU-177 can be used for tauopathies research.

Application

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Product Information

• Catalog No.: HY-151335
• CAS No.: 1160952-43-1
• Molecular Formula: C27H23NO8
• Molecular Weight: 489.47
• Purity: 99.98%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source