Keap1-Nrf2-IN-14

Overview

Keap1-Nrf2-IN-14 (compound 20c) is a KEAP1-NRF2 inhibitor that effectively disrupts the KEAP1-NRF2 interaction ( IC 50 =75 nM) with a K d value of 24 nM for KEAP1 . Keap1-Nrf2-IN-14 induces the expression of NRF2 target genes and enhances the downstream antioxidant and anti-inflammatory activities. Keap1-Nrf2-IN-14 can be used in the study of oxidative stress-related inflammation.

Application

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Product Information

• Catalog No.: HY-151362
• CAS No.: 1928782-31-3
• Molecular Formula: C30H29NO8S
• Molecular Weight: 563.62
• Purity: 98.08%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.44 mM); Clear solution
• Availability: In-stock

Source

Original product source