XAV-939

Overview

XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC 50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer , fibrotic diseases and conditions associated with low bone formation.

Application

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Product Information

• Catalog No.: HY-15147
• CAS No.: 284028-89-3
• Molecular Formula: C14H11F3N2OS
• Molecular Weight: 312.31
• Purity: 99.80%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 1.56 mg/mL (5.00 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source