(S)-GNE-140 (Compound 30-S) is the S-enantiomer of GNE-140 ( HY-118241 ). (S)-GNE-140 is an effective lactate dehydrogenase (LDH) inhibitor, with IC 50 values of 55 nM for LDHA and 140 nM for LDHB. (S)-GNE-140 can be used in cancer research.
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