PBRM1-BD2-IN-5

Overview

PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with K d values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC 50 value of 0.26 μM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-151532
• CAS No.: 2819989-61-0
• Molecular Formula: C15H13ClN2O
• Molecular Weight: 272.73
• Purity: 99.75%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 4 mg/mL (14.67 mM); Clear solution
• Availability: In-stock

Source

Original product source