Akt3 degrader 1

Overview

Akt3 degrader 1 (compound 12l) is a selective Akt3 degrader that overcomesOsimertinib ( HY-15772 )-induced resistance in H1975OR NSCLC cells. Akt3 degrader 1 also has anti-proliferative activity and significantly inhibits tumour growth in mice. Akt3 degrader 1 can be used in the study of drug-resistant non-small cell lung cancer .

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-151606
• CAS No.: 2836342-69-7
• Molecular Formula: C53H72N8O4
• Molecular Weight: 885.19
• Purity: 95.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source