TAK-960 monohydrochloride

Overview

TAK-960 monohydrochloride is an orally available, selective inhibitor of polo-like kinase 1 ( PLK1 ) , with an IC 50 of 0.8 nM. TAK-960 monohydrochloride also shows inhibitory activities against PLK2 and PLK3 , with IC 50 s of 16.9 and 50.2 nM, respectively. TAK-960 monohydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Polo-like Kinase (PLK)

Product Information

• Catalog No.: HY-15160C
• CAS No.: 2108449-45-0
• Molecular Formula: C27H35ClF3N7O3
• Molecular Weight: 598.06
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source