hCAIX-IN-16 (Compound 12d) is hCA IX inhibitor, with K i values of 190.0 and 187.9 nM for hCA IX and hCA XII , respectively. hCAIX-IN-16 can arrest the cell cycle of breast cancer MDA-MB-468 in G0-G1 and S phase and induce apoptosis . hCAIX-IN-16 shows good broad-spectrum anticancer activity and can be used for cancer research.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carbonic Anhydrase
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