FGFR2/3-IN-1

Overview

FGFR2/3-IN-1 is a potent and selective FGFR2 and FGFR3 ( FGFR ) inhibitor with IC 50 s of 1 nM and 0.5 nM, respectively. FGFR2/3-IN-1 displays >40-fold selectivity over FGFR1/FGFR4 and other kinome. FGFR2/3-IN-1 also inhibits FGFR3 V555L and V555M mutants with IC 50 s of 2.7 nM and 6.1 nM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FGFR

Product Information

• Catalog No.: HY-151903S
• CAS No.: 2640352-86-7
• Molecular Formula: C23H22D3N7O3
• Molecular Weight: 450.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source