YUKA1

Overview

YUKA1 is a potent and cell permeable Lysine demethylase 5A ( KDM5A ) inhibitor, with an IC 50 of 2.66 μM. YUKA1 has less inhibitory active on KDM5C ( IC 50 = 7.12 μM) and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 can increase H3K4me3 levels and inhibit cell proliferation. YUKA1 can be used for the research of cancer , such as lung and breast cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Demethylase

Product Information

• Catalog No.: HY-100764
• CAS No.: 708991-09-7
• Molecular Formula: C13H16N4O2S
• Molecular Weight: 292.36
• Purity: 99.15%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source