TRK II-IN-1

Overview

TRK II-IN-1 is a potent type II TRK inhibitor, with IC 50 s of 3.3, 6.4, 4.3 and 9.4 nM, for TRKA/B/C and TRKA G667C , respectively. TRK II-IN-1 also inhibits FLT3 , RET , and VEGFR2 with IC 50 s of 1.3, 9.9, and 71.1 nM, respectively. TRK II-IN-1 can be used for the research of TRK driven cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > RET

Product Information

• Catalog No.: HY-151945
• CAS No.: 2904690-41-9
• Molecular Formula: C29H31F3N8O
• Molecular Weight: 564.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source