ZC0109

Overview

ZC0109 is a dual inhibitor of IDO1 and thioredoxin reductase 1 ( TrxR1 ) with IC 50 s of 50 nM and 3.0 μM, respectively. ZC0109 induces ROS accumulation and cell cycle arrest at G1/S phase, thus leads to cancer cells apoptosis .

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO) | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-151978
• CAS No.: 3037850-79-3
• Molecular Formula: C22H20BrFN8O4S
• Molecular Weight: 591.41
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source