Glibenclamide

Overview

Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein . Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy .

Application

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Product Information

• Catalog No.: HY-15206
• CAS No.: 10238-21-8
• Molecular Formula: C23H28ClN3O5S
• Molecular Weight: 494.00
• Purity: 99.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.06 mM); Clear solution
• Availability: In-stock

Source

Original product source