(±)-Aiphanol

Overview

(±)-Aiphanol is a newly discovered stilbenolignan analog. (±)-Aiphanol exhibits significant anti-inflammatory activity, acting through inhibition of COX-1 and COX-2 . The inhibitory effect on COX-1 (IC 50 = 1.9 μM) is particularly strong, while the effect on COX-2 (IC 50 = 9.9 μM) is relatively weak.(±)-Aiphanol effectively inhibits VEGFR2 ( IC 50 =0.92 μM). (±)-Aiphanol blocks angiogenesis and promotes apoptosis through inhibition of VEGFR2 and COX2 activity. (±)-Aiphanol is orally active.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > COX | Products > Signaling Pathways > VEGFR

Product Information

• Catalog No.: HY-152120
• CAS No.: 578020-29-8
• Molecular Formula: C25H24O8
• Molecular Weight: 452.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source