XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7 , with an IC 50 of 3.4 nM, and also shows potent effect with IC 50 s of 215, 42 nM on CK2 , PIM1 , respectively, and an EC 50 of 118 nM on pMCM.
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