GS-6201

Overview

GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors ( K i =22 nM). GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse. GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice.

Application

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Product Information

• Catalog No.: HY-10081
• CAS No.: 752222-83-6
• Molecular Formula: C21H21F3N6O2
• Molecular Weight: 446.43
• Purity: 98.47%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2 mg/mL (4.48 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source