Mefatinib

Overview

Mefatinib (Mifanertinib dimaleate) is an orally active EGFR and HER2 kinase inhibitor with IC 50 values of 0.4 nM and 11.7 nM, respectively. Mefatinib inhibits tumor growth in mouse models of lung cancer xenografts that overexpress EGFR/HER2, carry EGFR mutations, or carry Erlotinib ( HY-50896 )-resistant EGFR double mutations. Mefatinib can be used for the research of advanced EGFR-mutant non-small cell lung cancer .

Application

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Product Information

• Catalog No.: HY-152852A
• CAS No.: 1989592-50-8
• Molecular Formula: C29H27ClF3N5O10
• Molecular Weight: 698.00
• Purity: 98.90%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source