Futibatinib

Overview

Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM).

Application

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Product Information

• Catalog No.: HY-100818
• CAS No.: 1448169-71-8
• Molecular Formula: C22H22N6O3
• Molecular Weight: 418.45
• Purity: 99.90%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 2.08 mg/mL (4.97 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source