AMG 487

Overview

AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 ( CXCR3 ) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC 50 s of 8.0 and 8.2 nM, respectively.

Application

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Product Information

• Catalog No.: HY-15319
• CAS No.: 473719-41-4
• Molecular Formula: C32H28F3N5O4
• Molecular Weight: 603.59
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (4.14 mM); Clear solution
• Availability: In-stock

Source

Original product source