SLMP53-2

Overview

SLMP53-2 is a mutant p53 reactivator. SLMP53-2 restores wild-type-like conformation and DNA-binding ability of mutp53-Y220C by enhancing its interaction with the Hsp70 , leading to the reestablishment of p53 transcriptional activity. SLMP53-2 can induce cell cycle arrest, apoptosis and endoplasmic reticulum (ER) stress. SLMP53-2 exhibits antitumor activity.

Application

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Product Information

• Catalog No.: HY-153202
• CAS No.: 1826116-38-4
• Molecular Formula: C26H22N2O2
• Molecular Weight: 394.47
• Purity: 99.96%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (12.68 mM); Clear solution
• Availability: In-stock

Source

Original product source