QR-6401

Overview

QR-6401 is an orally active and selective macrocyclic CDK2 inhibitor with IC 50 values of 0.37, 10, 22, 34 and 45 nM for CDK2/E1 , CDK9/T1 , CDK1/A2 , CDK6/D3 and CDK4/D1 , respectively. QR-6401 has potent antitumor activity in an OVCAR3 ovarian cancer xenograft model. QR-6401 has the potential to be used in the study of cancer .

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-153221
• CAS No.: 2845096-18-4
• Molecular Formula: C19H23N5O3
• Molecular Weight: 369.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source