(S)-TNG260

Overview

(S)-TNG260 is an isomer of TNG260 ( HY-153358 ). TNG260 is a CoREST selective deacetylase (CoreDAC) inhibitor. TNG260 inhibits HDAC1 with 10-fold selectivity over HDAC3 . TNG260 causes HDAC1 inhibition and reverses anti-PD1 resistance driven by STK11 deletion. TNG260 reduces intratumoral infiltration of neutrophils. TNG260 exhibits immune-mediated cell killing.

Application

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Product Information

• Catalog No.: HY-153358A
• CAS No.: 2935964-93-3
• Molecular Formula: C20H18FN3O2S
• Molecular Weight: 383.44
• Purity: 98.39%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source