Fosigotifator THAM sodium

Overview

Fosigotifator (ABBV-CLS-7262) THAM sodium is a brain penetrant, orally active EIF2b ( eukaryotic initiation factor ) activator. Fosigotifator THAM sodium stabilizes the elF2B complex and boosts the activity, including that of complexes carrying pathogenic vanishing white matter (VWM) mutations. Fosigotifator THAM sodium is an integrated stress response inhibitor (ISRI). Fosigotifator THAM sodium can be used for amyotrophic lateral sclerosis research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Amyotrophic Lateral Sclerosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Signaling Pathways > Eukaryotic Initiation Factor (eIF)

Product Information

• Catalog No.: HY-153399A
• CAS No.: 2945073-88-9
• Molecular Formula: C29H37Cl2F2N3NaO12P
• Molecular Weight: 782.48
• Purity: 99.98%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source