VUBI1 analogue-1 (compound 79) is a VUBI1 ( HY-111671 ) analogue. VUBI1 (SOS1 activator 1) is a SOS1 activator with a K d of 44 nM. VUBI1 analogue-1 can be used to synthesize (4S)-PROTAC SOS1 degrader-1 ( HY-144657 ) [1] .
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