SHP2-IN-14

Overview

SHP2-IN-14 (compound 27) is an orally active and potent SHP2 allosteric inhibitor ( IC 50 =7 nM) with anti-tumor activity. SHP2-IN-14 inhibits tumor progression in NCI-H358 tumor bearing mice, exhibits good pharmacokinetic characteristics and safty.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2

Product Information

• Catalog No.: HY-153699
• CAS No.: 2673400-91-2
• Molecular Formula: C22H20Cl2N8O
• Molecular Weight: 483.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source