PI5P4Kγ-IN-1 is an ATP-competitive, highly selective chemical probe for PI5P4Kγ , with a K d of 19 nM and an IC 50 of 67 nM. PI5P4Kγ-IN-1 effectively inhibits PI5P4Kγ function and activates the mTORC1 signaling pathway in cells. PI5P4Kγ-IN-1 can be used in studies related to diseases such as breast cancer .
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