Alcudacigib

Overview

Alcudacigib (ASP1570; DGKζ-IN-1) is an orally active diacylglycerol kinase ζ ( DGKζ ) inhibitor, with an IC 50 of 4.7 nM against human DGKζ and an IC 50 of 3.0 nM against mouse DGKζ . Alcudacigib selectively inhibits the kinase activity of DGKζ and induces proteasome-dependent degradation of DGKζ protein. Alcudacigib enhances the anti-tumor functions of T cells and NK cells. Alcudacigib can be used for the research of advanced/metastatic solid tumors.

Application

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Product Information

• Catalog No.: HY-153793
• CAS No.: 2660218-70-0
• Molecular Formula: C27H25F3N6O2S
• Molecular Weight: 554.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source