Zamaporvint

Overview

Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt . Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research.

Application

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Product Information

• Catalog No.: HY-153855
• CAS No.: 1900754-56-4
• Molecular Formula: C21H16F3N7O
• Molecular Weight: 439.39
• Purity: 99.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source