PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction ( IC 50 =0.029 μM), with a selected binding affinity with PD-L1 ( K D =0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment.
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