FGFR-IN-11

Overview

FGFR-IN-11 (compound I-5) is an orally active and covalent FGFR inhibitor with IC 50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (FGFR4), respectively. FGFR-IN-11 inhibits multiple cancer cell proliferation with nanomolar activity. FGFR-IN-11 inhibits tumor growth significantly in xenograft mice models.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FGFR

Product Information

• Catalog No.: HY-155028
• CAS No.: 2658488-68-5
• Molecular Formula: C28H29ClN4O4
• Molecular Weight: 521.01
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source