Tubulin inhibitor 35

Overview

Tubulin inhibitor 35 (compound 6b) is a dual inhibitor of topoisomerase I ( IC 50 =~50 μM) and tubulin polymerization ( IC 50 =5.69 μM). Tubulin inhibitor 35 inhibits migration and invasion of MGC-803 and RKO cell lines，and induces apoptosis via arresting cell cycle at G2/M phase. Tubulin inhibitor 35 exhibis potent efficacy in gastrointestinal tumor inhibiton (inhibits MGC-803 ( IC 50 =0.09 μM) and RKO ( IC 50 =0.2 μM) cell lines).

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-155073
• CAS No.: 2247047-77-2
• Molecular Formula: C21H21N3O
• Molecular Weight: 331.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source