ML-9

Overview

ML-9 is a selective and potent inhibitor of Akt kinase , inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 inhibits inhibits MLCK, PKA and PKC activity with K i values of 4, 32 and 54 μM, respectively. ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Myosin

Product Information

• Catalog No.: HY-100932
• CAS No.: 105637-50-1
• Molecular Formula: C15H18Cl2N2O2S
• Molecular Weight: 361.29
• Purity: 99.86%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.76 mM); Clear solution
• Availability: In-stock

Source

Original product source