CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor ( IC 50 : 6.72 μM for human CES2 ). CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan ( HY-16562 )-induced delayed diarrhea and DSS-induced ulcerative colitis.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carboxylesterase (CES)
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