FLT3/CHK1-IN-1

Overview

FLT3/CHK-IN-1 (Compound 18) is a dual inhibitor of FLT3/CHK1. FLT3/CHK-IN-1 is more than 1700 times more selective to c-KI T and greatly reduces hERG affinity with an IC 50 value of 58.4 μM. FLT3/CHK-IN-1 inhibits tumor growth in mouse xenotransplantation models inoculated with MV-4-11 cells.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FLT3

Product Information

• Catalog No.: HY-155195
• CAS No.: 2991054-23-8
• Molecular Formula: C25H33F3N6O2
• Molecular Weight: 506.56
• Purity: 99.37%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: 2.5 mg/mL (4.94 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source