A09-003

Overview

A09-003 is a CDK-9 inhibitor ( IC 50 : 16 nM). A09-003 inhibits leukemia cell proliferation (IC 50 : 1.90, 0.86, 2.49, 1.84, 0.48 μM for BDCM, Molm-14, THP-1, U937, MV4-11 cells). A09-003 induces apoptosis and decreases Mcl-1 expression through Thr163 dephosphorylation.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-155245
• CAS No.: 2911646-14-3
• Molecular Formula: C23H26N4O
• Molecular Weight: 374.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source