MAO A/HSP90-IN-2

Overview

MAO A/HSP90-IN-2 (compound 4-C) is a dual inhibitor of HSP90 and MAO A with the IC 50 values of 0.016 and 4.58 μM, respectively. MAO A/HSP90-IN-2 increases HSP70 expression and reduces HER2 and phospho-Akt expression, and decreases IFN-γ induced PD-L1 expression in GL26 cells. MAO A/HSP90-IN-2 inhibits the growth of Temozolomide ( HY-17364 ) -sensitive and -resistant GBM cells, colon cancer , leukemia, non-small cell lung and other cancers, and has potential to inhibit tumor immune escape [1] .

Application

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Product Information

• Catalog No.: HY-155580
• CAS No.: 2927489-99-2
• Molecular Formula: C25H31ClN2O4
• Molecular Weight: 458.98
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source