Lepadin E

Overview

Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > ACSL Family | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-155851
• CAS No.: 444914-19-6
• Molecular Formula: C26H47NO3
• Molecular Weight: 421.66
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source