IV-255

Overview

IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain. IV-255 increases the extent of DNA damage induced by Temozolomide ( HY-17364 ) and Bleomycin ( HY-108345 ). IV-255 inhibits the invasiveness of GBM cells. IV-255 enhances Temozolomide -induced cell death and the apoptosis-inducing activity of Temozolomide .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-155888
• CAS No.: 3057089-47-8
• Molecular Formula: C19H19F2N3O2
• Molecular Weight: 359.37
• Purity: 99.28%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (6.96 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source