Cyano-myracrylamide

Overview

Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 ( zDHHC20 ) with an IC 50 value of 1.35 µM. Cyano-myracrylamide also inhibits the S-Acylation of EGFR and CD36. Cyano-myracrylamide also inhibits S-acylation of Legionella E3 ligase GobX, MyD88 , and Ras , which are substrates of zDHHC20, zDHHC9, and zDHHC6, respectively, in HEK293T cells expressing recombinant Legionella GobX, recombinant human MyD88 , or endogenous Ras .

Application

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Product Information

• Catalog No.: HY-155938
• CAS No.: 2801702-34-9
• Molecular Formula: C19H34N2O
• Molecular Weight: 306.49
• Purity: 98.13%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.16 mM); Clear solution
• Availability: In-stock

Source

Original product source