VISTA-IN-2

Overview

VISTA-IN-2 (Compound 1) is an inhibitor of V-domain Ig suppressor of T-cell activation ( VISTA ) . VISTA-IN-2 induces VISTA degradation in cells through an autophagic mechanism. VISTA-IN-2 rescues VISTA-mediated immunosuppression, and enhances antitumor activity of immune cells. VISTA-IN-2 also activates the antitumor immunity and inhibits tumor growth in a CT26 mouse model.

Application

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Product Information

• Catalog No.: HY-155971
• CAS No.: 2614183-36-5
• Molecular Formula: C23H23N3O
• Molecular Weight: 357.45
• Purity: 98.91%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (6.99 mM); Clear solution
• Availability: In-stock

Source

Original product source