YCH1899

Overview

YCH1899 is an orally active PARP inhibitor, with an IC 50 < 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib ( HY-10162 )-resistant and Talazoparib ( HY-16106 )-resistant Capan-1 cells (Capan-1/OP and Capan-1/TP cells) , with IC 50 values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats.

Application

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Product Information

• Catalog No.: HY-155993
• CAS No.: 3032451-66-1
• Molecular Formula: C25H18BrFN6O3
• Molecular Weight: 549.35
• Purity: 99.39%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2 mg/mL (3.64 mM); Clear solution
• Availability: In-stock

Source

Original product source