PI3Kα-IN-13

Overview

PI3Kα-IN-13 (Compound 18a) is a PI3Kα inhibitor ( IC 50 : 2.5 nM). PI3Kα-IN-13 induces tumor cell apoptosis . PI3Kα-IN-13 inhibits cancer cell proliferation with IC 50 s of 0.75 μM (MCF-7), 3.79 μM (HCT-116), 13.71 μM (MDA-MB-231), 9.85 μM (SW620), respectively. PI3Kα-IN-13 inhibits tumor cell colony formation, migration and invasion.

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-156018
• CAS No.: 2955529-67-4
• Molecular Formula: C21H19N5O3
• Molecular Weight: 389.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source