HCAR2 agonist 1

Overview

HCAR2 agonist 1 (Compound 9n) is a G i protein-biased allosteric modulator of HCAR2 . HCAR2 agonist 1 activates the G i protein signaling pathway. HCAR2 agonist 1 shows anti-inflammatory effect, and reduces mRNA level of pro-inflammatory cytokine (TNF-α, IL-1β, IL-6 , and MCP-1). HCAR2 agonist 1 enhances anti-inflammatory effects of orthosteric agonists in the mouse model of colitis.

Application

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Product Information

• Catalog No.: HY-156025
• CAS No.: 1066676-21-8
• Molecular Formula: C26H28N4O2
• Molecular Weight: 428.53
• Purity: 99.11%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.67 mM); Clear solution
• Availability: In-stock

Source

Original product source