SIRT6-IN-3

Overview

SIRT6-IN-3 (compound 8a) is a selective inhibitor of SIRT6 ( IC 50 =7.49 μM). SIRT6-IN-3 inhibits pancreatic ductal adenocarcinoma (PDAC) cells proliferation and induces apoptosis . SIRT6-IN-3 increases the sensitivity of cancer cells to gemcitabine ( HY-17026 ) via blocking the DNA damage repair pathway. SIRT6-IN-3 is used in pancreatic cancer research.

Application

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Product Information

• Catalog No.: HY-156027
• CAS No.: 3023471-40-8
• Molecular Formula: C21H30Br3ClN6S
• Molecular Weight: 673.73
• Purity: 98.19%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Availability: In-stock

Source

Original product source