PDK-IN-2

Overview

PDK-IN-2 (Compound 1F) is a PDK inhibitor ( IC 50 : 68 nM). PDK-IN-2 inhibits the cellular expression of PDK1 and PDK4. PDK-IN-2 enhances mitochondrial bioenergetics, attenuates glycolytic phenotypes, and induces cell apoptosis in the mitochondrial pathway. PDK-IN-2 inhibits tumor growth in 4T1 syngeneic mice model.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PDHK | Products > Signaling Pathways > Mitochondrial Metabolism

Product Information

• Catalog No.: HY-156109
• CAS No.: 3032446-61-7
• Molecular Formula: C17H23AsCl2N2O2S2
• Molecular Weight: 497.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source