MIPS-21335 is a PI3KC2α inhibitor with an IC 50 of 7 nM. MIPS-21335 also inhibits PI3KC2β , p110α, p110β and p110δ, with IC 50 values of 43, 140, 386 and 742 nM, respectively. MIPS-21335 has antithrombotic effect. MIPS-21335 can be used for the researches of cardiovascular disease and metabolic disease , such as thrombosis and hyperlipidemia.
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