Multi-kinase-IN-6

Overview

Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that shows good enzyme inhibitory activity against TrkA , ALK2 , c-KIT , EGFR , PIM1 , CK2α , CHK1 , and CDK2 . Multi-kinase-IN-6 reveals antiproliferative activity against MCF7, HCT116 and EKVX with IC 50 values of 3.36 μM, 1.40 μM and 3.49 μM, respectively. Multi-kinase-IN-6 shows cell cycle arrest at the G1/S phase and G1 phase in MCF7 and HCT116 cells with good apoptotic effect.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Pim | Products > Signaling Pathways > Casein Kinase | Products > Signaling Pathways > Checkpoint Kinase (Chk) | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > Anaplastic lymphoma kinase (ALK)

Product Information

• Catalog No.: HY-156470
• CAS No.: 3009081-73-3
• Molecular Formula: C17H15N5O2
• Molecular Weight: 321.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source