TT-012

Overview

TT-012 is a MITF inhibitor with a human MITF IC 50 of 13.1 nM and a human MITF K d value of 15.5 nM. TT-012 reduces mRNA levels of MITF downstream genes linked to melanosome biogenesis, cell survival, and proliferation, and upregulates cell cycle-inhibiting genes. TT-012 can be used for the research of melanoma [1] [2] [3] .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Melanoma | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Microphthalmia Associated Transcription Factor (MITF)

Product Information

• Catalog No.: HY-156483
• CAS No.: 1164471-33-3
• Molecular Formula: C19H15N3O4
• Molecular Weight: 349.34
• Purity: 99.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (7.16 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source