ETC-168 is a selective and oral active MNK inhibitor with the IC 50 values of 23 and 43 nM against MNK1 and MNK2 , respectively. ETC-168 shows antiproliferative efficacy in vivo and in vitro .
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MNK
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