Rocbrutinib

Overview

Rocbrutinib is an orally available, highly selective Bruton's tyrosine kinase ( BTK ) inhibitor, with an IC 50 of 0.11 nM against wild-type BTK and an IC 50 of 1.0 nM against C481S-mutated BTK . Rocbrutinib reduces the viability of leukemia cells, induces cytotoxicity and inhibits cell migration. Rocbrutinib can be used in research related to chronic lymphocytic leukemia, non-Hodgkin's lymphoma and mantle cell lymphoma.

Application

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Product Information

• Catalog No.: HY-156640
• CAS No.: 2485861-07-0
• Molecular Formula: C42H51N9O5
• Molecular Weight: 761.91
• Purity: 99.76%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source